--- title: R&D of novel antibiotics needed to treat life-threatening infections as AMR increases description: A serious public health threat of the 21st century, Antimicrobial Resistance (AMR) – also known as antibiotic resistance means PCR UTI testing is a must. image: https://blog.acutis.com/hubfs/Imported_Blog_Media/2b6d08_aa6bad8c28f140188847c40f473f43ee~mv2.jpeg --- [Skip to content](https://blog.acutis.com/post/r-d-of-novel-antibiotics-needed-to-treat-life-threatening-infections-as-amr-increases#main-content) Close - About - [What is Acutis?](https://acutis-21140295.hs-sites.com/what-is-acutis) - [Our Team](https://acutis-21140295.hs-sites.com/we-are-acutis) - [Guiding Principles](https://acutis-21140295.hs-sites.com/guiding-principles) - [Compliance](https://acutis-21140295.hs-sites.com/en/compliance) - [Accreditations](https://acutis-21140295.hs-sites.com/accreditations) - [Careers](https://acutis-21140295.hs-sites.com/careers) - [Continuing Education](https://acutis-21140295.hs-sites.com/webinars-symposium) - 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[Insights](https://blog.acutis.com) - [Contact](https://acutis-21140295.hs-sites.com/contact) PHONE HOTLINE: [844-522-8847](tel:+1844-522-8847)E-MAIL: [service@acutis.com](mailto:service@acutis.com) [i-Acutis](https://acutis.careevolve.com/doctors/framepage.asp) ![PCR UTI testing](https://blog.acutis.com/hs-fs/hubfs/Imported_Blog_Media/2b6d08_aa6bad8c28f140188847c40f473f43ee~mv2.jpeg?width=300&name=2b6d08_aa6bad8c28f140188847c40f473f43ee~mv2.jpeg) [Acutis](https://blog.acutis.com/author/acutis)Apr 8, 2022 12:00:00 AM1 min read # R&D of novel antibiotics needed to treat life-threatening infections as AMR increases [Previous](https://blog.acutis.com/post/a-steep-rise-in-hospitalizations-of-children-due-to-omicron) [Next](https://blog.acutis.com/post/std-awareness-week) ![](https://blog.acutis.com/hubfs/Imported_Blog_Media/2b6d08_aa6bad8c28f140188847c40f473f43ee~mv2-1.jpeg) A serious, complex, leading public health threat of the 21st century, [Antimicrobial Resistance (AMR)](https://www.acutis.com/post/antimicrobial-resistance-a-major-threat-to-public-health) – also known as antibiotic resistance – is projected to induce 10 million deaths per year by 2050. Despite the [global rise of AMR](https://www.acutis.com/post/fatalities-caused-by-antimicrobial-resistance-amr-surpass-deaths-related-to-hiv) and the emergence of several multi-drug resistant pathogens (MDR), investment in the Research & Development of novel antimicrobials capable of treating life-threatening infections caused by MDR pathogensz is lacking. If left unchecked, the spread of antimicrobial resistance could lead to several MDR pathogens emerging, some of which could be many times more lethal than they are today. New antibiotics are needed urgently to tackle existing and emerging multi-drug resistant bacteria. Unfortunately, the massive rise of AMR cannot be counteracted by the current low development pace of therapeutics. Only less than 25% of existing drugs in the clinical development pipeline represent a novel class or act through a novel mechanism – none of which are potentially active against resistant Gram-negative bacteria or [critical threat pathogens](https://www.who.int/news/item/27-02-2017-who-publishes-list-of-bacteria-for-which-new-antibiotics-are-urgently-needed) defined by the World Health Organization. A strategic blueprint to substantially improve our ability to discover and develop novel class antibiotics, particularly in the fields of natural-product-derived and synthetic small molecules, which have massive potential for newer agents with innovative chemistry and modes of action, is needed right away. At Acutis, we offer [PCR-guided antimicrobial sensitivity information](https://www.acutis.com/molecular-tests-infectious-disease) for our clients to assist physicians in determining the best course of treatment for their patients. Selecting the correct antibiotic for a patient is the best way to overcome antimicrobial resistance and enables us to be part of the global effort in overcoming this public health obstacle. [**Visit Nature to access the full article.**](https://www.nature.com/articles/s41570-021-00313-1) ![avatar](https://blog.acutis.com/hs-fs/hubfs/Sales%20materials%202023/Brand/logo-acutis%20HD-2022-1.png?width=290&name=logo-acutis%20HD-2022-1.png) #### [Acutis](https://blog.acutis.com/author/acutis) Our team of scientific experts is here to help you understand the trends in infectious disease, clinical toxicology, and Biosciences that are happening in the world. [mailto:service@acutis.com](mailto:service@acutis.com) ## RELATED ARTICLES [![Acutis-white](https://info.acutis.com/hs-fs/hubfs/Acutis-white.png?width=100&name=Acutis-white.png)](https://www.acutis.com/) **Insights. Answers. 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Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.© 2026 Acutis Diagnostics ```json { "@context" : "https://schema.org", "@type" : "Organization", "address" : { "@type" : "PostalAddress", "addressCountry" : "", "addressLocality" : "Hicksville", "addressRegion" : "NY", "postalCode" : "11801", "streetAddress" : "400 Karin Lane" }, "email" : "service@acutis.com", "knowsLanguage" : "en", "logo" : { "@type" : "ImageObject", "url" : "https://f.hubspotusercontent40.net/hubfs/21140295/logo-Acutis%20HD-2.webp" }, "name" : "Acutis Diagnostics Inc.", "telephone" : "844-522-8847", "url" : "https://blog.acutis.com/post/r-d-of-novel-antibiotics-needed-to-treat-life-threatening-infections-as-amr-increases" } ``` ```json { "@context" : "https://schema.org", "@type" : "BlogPosting", "abstract" : "A serious public health threat of the 21st century, Antimicrobial Resistance (AMR) – also known as antibiotic resistance means PCR UTI testing is a must.", "author" : { "@type" : "Person", "name" : "Acutis" }, "dateModified" : "April 6, 2023 12 AM", "datePublished" : "April 8, 2022 4 AM", "headline" : "R&D of novel antibiotics needed to treat life-threatening infections as AMR increases", "image" : "https://info.acutis.com/hubfs/Imported_Blog_Media/2b6d08_aa6bad8c28f140188847c40f473f43ee~mv2.jpeg", "inLanguage" : "en", "keywords" : "[NEWS]", "mainEntityOfPage" : { "@type" : "WebPage" }, "name" : "R&D of novel antibiotics needed to treat life-threatening infections as AMR increases", "publisher" : { "@type" : "Organization", "logo" : { "@type" : "ImageObject", "url" : "https://f.hubspotusercontent40.net/hubfs/21140295/logo-Acutis%20HD-2.webp" }, "name" : "Acutis Diagnostics Inc." }, "text" : "A serious, complex, leading public health threat of the 21st century, Antimicrobial Resistance (AMR) – also known as antibiotic resistance – is projected to induce 10 million deaths per year by 2050. Despite the global rise of AMR and the emergence of several multi-drug resistant pathogens (MDR), investment in the Research & Development of novel antimicrobials capable of treating life-threatening infections caused by MDR pathogensz is lacking. If left unchecked, the spread of antimicrobial resistance could lead to several MDR pathogens emerging, some of which could be many times more lethal than they are today. New antibiotics are needed urgently to tackle existing and emerging multi-drug resistant bacteria. Unfortunately, the massive rise of AMR cannot be counteracted by the current low development pace of therapeutics. Only less than 25% of existing drugs in the clinical development pipeline represent a novel class or act through a novel mechanism – none of which are potentially active against resistant Gram-negative bacteria or critical threat pathogens defined by the World Health Organization. A strategic blueprint to substantially improve our ability to discover and develop novel class antibiotics, particularly in the fields of natural-product-derived and synthetic small molecules, which have massive potential for newer agents with innovative chemistry and modes of action, is needed right away. At Acutis, we offer PCR-guided antimicrobial sensitivity information for our clients to assist physicians in determining the best course of treatment for their patients. Selecting the correct antibiotic for a patient is the best way to overcome antimicrobial resistance and enables us to be part of the global effort in overcoming this public health obstacle. Visit Nature to access the full article.", "url" : "https://blog.acutis.com/post/r-d-of-novel-antibiotics-needed-to-treat-life-threatening-infections-as-amr-increases", "wordCount" : "925" } ``` ```json { "@context" : "https://schema.org", "@type" : "BlogPosting", "author" : { "@type" : "Person", "name" : "Acutis", "url" : "https://blog.acutis.com/author/acutis" }, "dateModified" : "2023-04-06T00:55:57.046Z", "datePublished" : "2022-04-08T04:00:00.000Z", "headline" : "R&D of novel antibiotics needed to treat life-threatening infections as AMR increases", "image" : [ "https://blog.acutis.com/hubfs/Imported_Blog_Media/2b6d08_aa6bad8c28f140188847c40f473f43ee~mv2.jpeg" ], "mainEntityOfPage" : { "@id" : "https://blog.acutis.com/post/r-d-of-novel-antibiotics-needed-to-treat-life-threatening-infections-as-amr-increases", "@type" : "WebPage" }, "publisher" : { "@type" : "Organization", "logo" : { "@type" : "ImageObject", "url" : "https://blog.acutis.com/hubfs/logo-Acutis%20HD-2.webp" }, "name" : "Acutis Diagnostics Inc. | Acutis Biosciences" } } ```